Prescribing Details
Description
Nemotis is a preparation of Faropenem which is a bactericidal with a strong affinity for the penicillin binding proteins of the bacterial cell wall. Faropenem acts by inhibiting the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of gram-positive bacteria. Faropenem is resistant to hydrolysis by many beta-lactamases and active against many gram-positive and gram-negative aerobes and anaerobes.
Uses
No Data
Indications
Nemotis is indicated for treatment of-
• Urinary tract infections
• Upper and lower respiratory tract infections
• Ear, nose and throat (ENT) infections
• Skin and skin structure infections
• Secondary infection of extemal wounds or surgical wound
• Gynecological infections
Dosage and administration
Route of adminisration: Nemotise should be administered in oral route.
| Indication | Dose |
|---|---|
| Urinary tract infections | 200 mg t.i.d., can be increased to 300 mg t.i.d. |
| Lower respiratory tract infections | 200 mg t.i.d., can be increased to 300 mg t.i.d. |
| Upper respiratory tract infections | 150 mg t.i.d., can be increased to 200 mg t.i.d. |
| Skin and skin structure infections | 150 mg t.i.d., can be increased to 200 mg t.i.d. |
| ENT infections | 200 mg t.i.d., can be increased to 300 mg t.i.d. |
| Gynecological infections | 150 mg t.i.d., can be increased to 200 mg t.i.d. |
Use in pregnancy & lactation
Pregnancy: There are no adequate and well-controlled studies in pregnant women with faropenem.
Lactation: Faropenem is excreted in human milk. The developmental and health benefits of breastfeeding
should be considered along with the mother's clinical need and any potential adverse effects on the
breastfed infant from faropenem or from the underlying matemal condition.
Use in children and adolescents
Safety and effectiveness in children and adolescents have not been established.
Geriatric use
Precautions
Caution should be taken in patients with family history of atopy, with renal impairment, elderly patients and in patients with poor oral intake or poor general state.
Side effects
The most common side effects are diarrhea, nausea, vomiting, headache and abdominal pain.
Contraindications
It is contraindicated in patients with history of known hypersensitivity to faropenem or to other drugs in the same class or any other components of this product.
Drug interactions
Drug interaction with medication: Caution should be taken in concomitant use with imipenem and cilastatin sodium combination, furosemide and sodium valproate.
Drug interaction with food and others: Not applicable.
Overdose
In case of overdose, treatment should be symptomatic and supportive measures instituted as required.
Preparation
No Data
Pharmaceutical precautions
No Data
Presentation
Nemotis 150 Tablet: Each coated tablet contains Faropenem 150 as Faropenem Sodium Hydrate INN.
Nemotis 200 Tablet: Each coated tablet contains Faropenem 200 as Faropenem Sodium Hydrate INN.
Package quantities
Storage
Store below 250 C in a dry place, protected from light. Keep away from the reach of children.
Packing
Nemotis 150 mg Tablet: Carton of 12 tablets in blister pack.
Nemotis 200 mg Tablet: Carton of 12 tablets in blister pack.
